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Thackray Lab Publications


Listed below are some recent peer-reviewed publications.  For a full list of publications, go to and search “Thackray, VG”.

Arroyo, P., Ho, B.S., Sau, L., Kelley, S.T., and Thackray, V.G. (2019) Letrozole Treatment of Pubertal Mice Results in Activational Effects on Reproduction, Metabolism and the Gut Microbiome. PLOS ONE 14(9):e0223274.

Torres, P.J., Skarra, D.V., Ho, B.S., Sau, L., Anvar, A.R., Kelley, S.T., and Thackray, V.G. (2019) Letrozole Treatment of Adult Female Mice Results in a Distinct Metabolic Phenotype and Changes in the Gut Microbiome. BMC Microbiology 19(1):57 doi: 10.1186/s12866-019-1425-7

Torres, P.J., Ho, B.S., Arroyo, P., Sau, L., Chen, A., Kelley, S.T., and Thackray, V.G. (2019) Exposure to a Healthy Gut Microbiome Improves Reproductive and Metabolic Phenotypes in a Mouse Model of Polycystic Ovary Syndrome. Endocrinology 160(5), 1193-1204

de la Cuesta-Zuluaga, J., Kelley, S.T., Chen, Y., Escobar, J.S., Mueller, N.T., Ley, R.E., McDonald, D., Huang, S., Swafford, A., Knight, R., and Thackray, V.G. (2019) Age- and Sex-Dependent Patterns of Gut Microbial Diversity in Human Adults. MSystems 14;4(4). pii: e00261-19 doi: 10.1128/mSystems.00261-1

Thackray, V.G. (2019) Sex, Microbes and Polycystic Ovary Syndrome. Trends in Endocrinology and Metabolism 30(1):54-65.

McDonald, D., Hyde E., Debelius, J . . .Thackray V.G. . . and Knight, R. (2018) American Gut: an Open Platform for Citizen-Science Microbiome Research. mSystems 3(3):e00031-18.

Torres, P.J., Siakowska, M., Banaszewska, B., Pawelczyk, L., Duleba, A.J., Kelley, S.T. and Thackray V.G. (2018) Gut Microbial Diversity in Women with Polycystic Ovary Syndrome Correlates with Hyperandrogenism. Journal of Clinical Endocrinology and Metabolism 103(4):1502-1511.

Skarra D.V., Hernandez-Carretero, A., Rivera, A.J., Anvar, A.R. and Thackray V.G. (2017) Hyperandrogenemia Induced by Letrozole Treatment of Pubertal Female Mice Results in Hyperinsulinemia Prior to Weight Gain and Insulin Resistance. Endocrinology 158(9):2988-3003.

Kelley, S.T., Skarra D.V., Rivera, A.J., and Thackray V.G. (2016) The Gut Microbiome Is Altered in a Letrozole-Induced Mouse Model of Polycystic Ovary Syndrome. PLOS ONE 11(1):e0146509.

Kauffman, A.S., Thackray V.G., Ryan, G.E., Tolson, K.P., Glidewell-Kenney, C.A., Semaan, S.J., Poling, M.C., Iwata, N., Breen., K.M., Duleba, A.J., Stener-Victorin, E., Shimasaki, S., Webster, N.J., and Mellon (2015) A Novel Letrozole Model Recapitulates Both the Reproductive and Metabolic Phenotypes of Polycytic Ovary Syndrome in Female Mice. Biology of Reproduction 93(3):69, 1-12.
Benson, C.A., Kurz, T.L. and Thackray, V.G. (2013) A Human FSHB Promoter SNP Associated With Low FSH Levels in Men Impairs LHX3 Binding and Basal FSHB Transcription. Endocrinology 154(9):3016-3021.