Kauffman Lab Publications
(**For a complete list of publications, search "Kauffman AS" on Pubmed)
Select Research Publications from past 5 years (updated Fall 2020; search "Kauffman AS" on Pubmed for a complete list of all articles)
Esparza LA, T Terasaka, MA Lawson, and AS Kauffman. Androgen suppresses in vivo and in vitro LH pulse secretion
and neural Kiss1 and Tac2 gene expression in female mice. Endocrinology, 161(12): bqaa191. 2020. [PMCID: PMC7671291]
Esparza LA, DA Schafer, BS Ho, VG Thackray, and AS Kauffman. Hyperactive LH pulses and
elevated kisspeptin and NKB gene expression in the arcuate nucleus of a PCOS
mouse model. Endocrinology, 161(4): 1-15, 2020. [PMCID: PMC7341557]
Tolson KP, N Marooki, JP De Bond, E Walenta, SBZ Stephens, RB
Liaw, R Savur, A Wolfe, DY Oh, JT Smith, and AS Kauffman. Conditional knockout of kisspeptin signaling in brown
adipose tissue increases metabolic rate and body temperature and lowers body
weight. FASEB Journal, 34(1): 107-121.
2020. [PMCID: PMC7202476]
Tolson KP, N Marooki, A Wolfe, JT Smith, and AS Kauffman. Cre/lox generation of a
novel whole-body Kiss1r KO mouse line recapitulates a hypogonadal, obese, and metabolically-impaired
phenotype. Molecular and Cellular Endocrinology,
498: 110559. 2019 [PMCID: PMC6814569]
Stephens SBZ*, N Di Giorgio*, RB Liaw, RA
Parra, JA Yang, N Chahal, VA Lux-Lantos, and AS Kauffman. Estradiol-dependent and -independent stimulation of Kiss1 expression in the amygdala, BNST, and
lateral septum of mice. Endocrinology.
159: 3389-3402, 2018. [PMCID: PMC6112601]
Yang JA, JK Hughes, RA Parra, KM Volk, and AS Kauffman. Stress rapidly suppresses in vivo LH pulses and increases activation of RFRP-3 neurons in
male mice. Journal of Endocrinology, 239:
339-350, 2018. [PMCID:
N Di Giorgio, RB Liaw, RA Parra, JA Yang, N Chahal, VA Lux-Lantos, and
AS Kauffman. Estradiol-dependent and -independent stimulation of Kiss1 expression in the amygdala, BNST, and
lateral septum of mice. Endocrinology.
[Accepted, In Press] 2018.
CI Song, J Hughes, MJ Kreisman, RA Parra, DJ Haisenleder, AS Kauffman, and KM Breen. Acute psychosocial stress inhibits LH
pulsatility and Kiss1 neuronal
activation in female mice. Endocrinology.
158: 3716-323, 2017.
Poling MC, E Luo, and AS Kauffman. Sex
differences in steroid receptor co-expression and circadian-timed activation of
kisspeptin and RFRP-3 neurons may contribute to the sexually dimorphic basis of
the LH surge. Endocrinology. 158: 3565-3578, 2017.
Stephens SBZ, ML Rouse, KP Tolson, RB. Liaw, RA Parra, N
Chahal, and AS Kauffman. Effects of selective deletion of tyrosine
hydroxylase from kisspeptin cells on puberty and reproduction in male and
female mice. eNeuro 4(3) e0150-17,
Tolson KP, C Garcia, I Delgado, N
Marooki, and AS Kauffman. Metabolism and energy expenditure, but not
feeding or glucose tolerance, are impaired in young Kiss1r KO female mice. Endocrinology, 157: 4192-4199. 2016.
SBZ, N Chahal, N Munaganuru, RA Parra, and AS
Kauffman. Estrogen stimulation of Kiss1
expression in the medial amygdala involves estrogen receptor α but not
estrogen receptor β. Endocrinology, 157:4021-4031. 2016.
Luo E, Stephens SBZ, Chiang S, N Munaganuru, AS Kauffman, and KM Breen.
Corticosterone blocks ovarian cyclicity and the LH surge via decreased
kisspeptin neuron activation in female mice.
Stephens SBZ, KP Tolson, ML Rouse, MC
Poling, MK Hashimoto-Partyka,
PL Mellon, and AS Kauffman. Absent progesterone signaling in
kisspeptin neurons disrupts the LH surge and impairs fertility in female mice. Endocrinology, 156: 3091-97. 2015.
Highlighted in News and Views section of the journal
Semaan SJ and AS Kauffman. Daily successive
changes in reproductive gene expression and neuronal activation in the
brains of pubertal female mice. Molecular
and Cellular Endocrinology, 401, 84-97, 2015.
Kauffman AS, VG Thackray, GE Ryan, KP Tolson, CA Glidewell-Kenney, SJ Semaan, MC Poling, N Iwata, KM Breen, AJ Duleba, E Stener-Victorin, S Shimasaki, NJ Webster, and PL Mellon. A novel letrozole model recapitulates both the reproductive and metabolic phenotypes of polycystic ovary syndrome in female mice. Biol Reprod, 93: 69: 1-12. 2015.