Welcome to the Thackray Lab
Polycystic ovary syndrome (PCOS)
is a common endocrine disorder in reproductive-aged women, with a
world-wide prevalence of 10-15%. In addition to a reproductive phenotype that
results in an increased risk of infertility, miscarriage and pregnancy
complications, a majority of women with PCOS have metabolic abnormalities that
result in an increased risk of type 2 diabetes, hypertension and non-alcoholic fatty liver disease. One of the main objectives of our research is to understand the
etiology and pathophysiology of PCOS using relevant mouse and tissue culture
models.